GenoMEL – Participants – Queensland, Australia


	GenoMEL is an international research consortium coordinated by the University of Leeds.


















































	Términos y condiciones Declaración de privacidad



	Translations by: Cuellar Francisco and Susana Puig

Title and address of our institution

Queensland Institute of Medical Research
300 Herston Rd
Herston
QLD 4029
Australia

Title and address of our group

Human Genetics, Genetic Epidemiology, and Cancer & Population Studies groups of the Queensland Institute of Medical Research

Melanocyte Biology and Pigmentation Genetics Group of the Institute for Molecular Bioscience

Viertel Centre for Research in Cancer Control Group of the Queensland Cancer Fund

The name, address and contact e-mail, tel of the group leaders

Dr Nicholas K. Hayward, PhD
Human Genetics Laboratory
Queensland Institute of Medical Research

E-mail: nickH@qimr.edu.au
Phone: 61-7-33620306
Fax: 61-7-38453508

Dr Nicholas G. Martin, PhD
Genetic Epidemiology Group
Queensland Institute of Medical Research

E-mail: nickM@qimr.edu.au
Phone: 61-7-33620278
Fax: 61-7-33620101

Dr Adele Green, MBBS, PhD
Cancer & Population Studies Group
Queensland Institute of Medical Research

E-mail: adeleG@qimr.edu.au
Phone: 61-7-33620324
Fax: 61-7-38453503

Dr Richard A. Sturm, PhD
Melanocyte Biology and Pigmentation Genetics Group
Institute of Molecular Bioscience
University of Queensland
306 Carmody Rd
St Lucia
QLD 4072

E-mail: r.sturm@mailbox.uq.edu.au
Phone: 61-7-33462038
Fax: 61-7-33462101

Dr Joanne Aitken
Viertel Centre for Research in Cancer Control
Queensland Cancer Fund
553 Gregory Tce
Fortitude Valley
QLD 4006

E-mail: joannea@qcfepi.org.au
Phone: 61-7-32582300
Fax: 61-7-32582310

A paragraph describing the group

The ‘Queensland’ group of the Consortium comprises principal investigators from various groups across a number of institutions - the Queensland Institute of Medical Research, the Institute of Molecular Bioscience and the Queensland Cancer Fund. Broadly, the Group is interested in identifying risk factors for melanoma through classical genetic epidemiologic analysis of several population-based cohorts of melanoma cases and controls. These include samples of children, adolescents, twins and men over 50 years of age with melanoma, as well as a sample of all melanoma cases ascertained in Queensland during the period 1982-1990.

The Group aims to identify both high and low penetrance genes for melanoma predisposition and is focussing initially on genes associated with variation in human pigmentation as candidates for the latter. Multiple-case families are being screened for mutations in the known melanoma susceptibility genes (encoding p16, p14 and CDK4), and those families in which mutations are not found are being utilized in conjunction with similar families from other groups within the Consortium in a genome-wide linkage scan for novel high penetrance melanoma genes.