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Publications |
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Basik M, Mousses S, Trent JM,
Integration of genomics technologies for accelerated cancer drug development,
BioTechniques, 35(3):580-2, 2003.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14513563 |
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Bergthorsson JT, Johannesdottir G, Arason A, Benediktsdottir KR, Agnarsson BA, Bailey- Wilson JE, Gillanders E, Smith J, Trent J, Barkardottir RB.
Analysis of HPC1, HPCX, and PCaP in Icelandic hereditary prostate cancer.
Human Genetics, 107(4):372-5, 2000.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11129338
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Bittner M, Meltzer P, Chen Y, Jiang Y, Seftor E, Hendrix M, Radmacher M, Simon R, Yakhini Z, Ben-Dor A, Dougherty E, Wang E, Marincola F, Gooden C, Lueders J, Glatfelter A, Pollock P, Gillanders E, Leja D, Dietrich K, Berens M, Alberts D, Sondak V, Hayward N, Trent J.
Molecular classification of cutaneous malignant melanoma by gene expression profiling.
Nature, 406:536-540, 2000.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10952317 |
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Bomprezzi R, Ringnér M, Kim S, Bittner ML, Khan J, Chen Y, Elkahloun A, Yu A, Bielekova B, Meltzer PS, Martin R, McFarland HF, Trent JM.
Gene expression profile in multiple sclerosis patients and healthy controls: Identifying pathways relevant to disease.
Hum Mol Genet 12(17): 2191-9, 2003.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12915464 |
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Carpten J, Nupponen N, Isaacs S, Sood R, Robbins C, Xu J, Faruque M, Moses T, Ewing T, Gillanders E, Hu P, Bujnovszky P, Makalowska I, Baffoe-Bonnie A, Faith D, Smith J, Stephan D, Wiley K, Brownstein M, Gildea D, Kelly B, Jenkins R, Hostetter G, Matikainen M, Schleutker J, Klinger K, Connors T, Xiang Y, Wang Z, De Marzo A, Papadopoulos N, Kallioniemi O-P, Burk R, Meyers D, Grönberg H, Meltzer P, Silverman R, Bailey-Wilson J, Walsh P, Isaacs W, Trent J.
Germline mutations in the ribonuclease L gene in families showing linkage with HPC1.
Nature Genetics, 30:181-184, 2002.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11799394 |
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Carpten JD, Makalowska I, Robbins CM, Scott N, Sood R, Connors TD, Bonner TI, Smith JR, Faruque MU, Stephan DA, Pinkett H, Morgenbesser SD, Su K, Graham C, Gregory SG, Williams H, McDonald L, Baxevanis AD, Klinger KW, Landes GM, Trent JM.
A 6-Mb high resolution physical and transcription map encompassing the hereditary prostate cancer 1(HPC1) region.
Genomics, 64:1-14, 2000.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10708513 |
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Carpten JD, Robbins CM, Villablanca A, Forsberg L, Presciuttini S, Bailey-Wilson J, Simonds WF, Gillanders EM, Kennedy AM, Chen JD, Agarwal SK, Sood R, Jones MP, Moses TY, Haven C, Petillo D, Leotlela PD, Harding B, Cameron D, Pannett AA, Hoog A, Heath H 3rd, James-Newton LA, Robinson B, Zarbo RJ, Cavaco BM, Wassif W, Perrier ND, Rosen IB, Kristoffersson U, Turnpenny PD, Farnebo LO, Besser GM, Jackson CE, Morreau H, Trent JM, Thakker RV, Marx SJ, Teh BT, Larsson C, Hobbs MR.
HRPT2, encoding parafibromin, is mutated in hyperparathyroidism-jaw tumor syndrome.
Nature Genetics, 32:676-80, 2002.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12434154 |
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Carr KM, Bittner M, Trent JM.
Gene-expression profiling in human cutaneous melanoma.
Oncogene, 22:3076-80, 2003.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12789283 |
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Douglas JA, Boehnke M, Gillanders E, Trent JM, Gruber SB.
Experimentally-derived haplotypes substantially increase the efficiency of linkage disequilibrium studies.
Nature Genetics, 28:361-4, 2001.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11443299 |
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Duggan DJ, Bittner M, Chen Y, Meltzer P, Trent JM.
Expression profiling using cDNA microarrays.
Nature Genetics, 21:10-14, 1999.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9915494 |
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Friedrichsen DM, Stanford JL, Isaacs SD, Janer M, Chang BL, Deutsch K, Gillanders E, Kolb S, Wiley KE, Badzioch MD, Zheng SL, Walsh PC, Jarvik GP, Hood L, Trent JM, Isaacs WB, Ostrander EA, Xu J.
Identification of a prostate cancer susceptibility locus on chromosome 7q11-21 in Jewish families.
Proc Natl Acad Sci U S A, 101:1939-44, 2004.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14769943 |
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Gillanders E, Appukuttan B, Juo SH, Freas-Lutz D, Ott S, Sood R, Van Auken A, Bailey-Wilson J, Wang X, Patel RJ, Robbins CM, Chung M, Annett G, Weinberg K, Borchert MS, Trent JM, Brownstein MJ, Stout JT.
Localization of a gene for Duane retraction syndrome to chromosome 2q31.
American Journal of Human Genetics, 65:1639-46, 1999.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10577917 |
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Gillanders E, Juo SH, Holland EA, Jones MP, Nancarrow D, Freas-Lutz D, Sood R, Faruque M, Markey C, Kefford R, Palmer J, Bergman W, Bishop DT, Tucker MA, Bressac-de Paillerets B, Hansson J, Stark M, Gruis N, Newton Bishop J, Goldstein AM, Bailey-Wilson JE, Mann GJ, Hayward N, Trent JM, The Melanoma Genetics Consortium.
Localization of a novel melanoma susceptibility locus to 1p22.
Am J Hum Genet, 73:301-13, 2003.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12844286 |
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Gillanders E, Lange E, Davis C, Brown W, Campbell J, Jones MP, Gildea D, Riedesel E, Albertus J, Freas-Lutz D, Markey C, Giri V, Dimmer J, Montie J, Trent J, Cooney K.
Genome-wide Scan for Prostate Cancer Susceptibility Genes using Families from the University of Michigan Prostate Cancer Genetics Project Finds Evidence for Linkage on Chromosome 17 near BRCA1.
Prostate, 57:326-34, 2003.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14601029 |
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Gillanders E, Schleutker J, Baffoe-Bonnie A, Kainu T, Jones MP, Markey C, Matikainen M, Koivisto P, Tammela T, Bailey-Wilson J, Trent J, Kallioniemi O.
A genome-wide scan for linkage in Finnish hereditary prostate cancer (HPC) families identifies putative novel susceptibility loci at 11q14 and 3p25-p26.
Prostate, 57:280-9, 2003.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14601024 |
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Gillanders E, Stephan DA, Vanderveen D, Freas-Lutz D, Wistow G, Baxevanis AD, Robbins CM, VanAuken A, Quesenberry MI, Bailey-Wilson J, Juo SH, Trent JM, Smith L, Brownstein MJ.
Progressive juvenile-onset punctate cataracts caused by mutation of the gammaD-crystallin gene.
Proc Natl Acad Sci U S A, 96:1008-12, 1999.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9927684 |
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Gillanders E, Wiklund F, Bergh A, Damber, J, Emanuelsson M, Göransson I, Jonsson B, Lindström F, Stenman E, Trent J and Grönberg H.
A Genomewide Scan of Swedish Families with Hereditary Prostate Cancer: Suggestive Evidence of Linkage at 5q11.2 and 19p13.3.
Prostate, 57:290-7, 2003.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14601025 |
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Gillanders E, Xu J, Isaacs S, Chang B, Wiley K, Zheng S, Jones MP, Gildea D, Riedesel E, Albertus J, Freas-Lutz D, Markey C, Meyers D, Walsh P, Trent J, Isaacs W.
Genome-wide scan for prostate cancer susceptibility genes in the Johns Hopkins hereditary prostate cancer families.
Prostate, 57:320-5, 2003.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14601028 |
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Hedenfalk I, Duggan D, Chen Y, Radmacher M, Bittner M, Simon R, Meltzer P, Gusterson B, Esteller M, Kallioniemi O, Wilfond B, Borg A, Trent J.
Gene expression profiles distinguish hereditary breast cancers.
N Engl J Med, 344:539-548, 2001.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11207349 |
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Hedenfalk, I, Ringner M, Ben-Dor, A, Yakhini, Z, Chen, Y, Chebil, G, Ach, R, Loman, N, Olsson, H, Meltzer, P, Borg, A, & Trent J.
Molecular classification of familial non-BRCA1/BRCA2 breast cancer.
Proc Natl Acad Sci U S A, 100:2532-2537, 2003.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12610208 |
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Huusko P, Juo SH, Gillanders E, Sarantaus L, Kainu T, Vahteristo P, Allinen M, Jones M, Rapakko K, Eerola H, Markey C, Vehmanen P, Gildea D, Freas-Lutz D, Blomqvist C, Leisti J, Blanco G, Puistola U, Trent J, Bailey-Wilson J, Winqvist R, Nevanlinna H, Kallioniemi OP.
Genome-wide scanning for linkage in Finnish breast cancer families.
Eur J Hum Genet, 12:98-104, 2004.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14560309 |
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Kainu T, Juo S-H, Desper R, Schäffer AA, Gillanders E, Rozenblum E, Freas-Lutz D, Weaver D, Stephan D, Bailey-Wilson J, Kallioniemi O, Tirkkonen M, Syrjäkoski K, Kuukasjärvi T, Koivisto P, Karhu R, Holli K, Arason A, Johannesdottir G, Bergthorsson JT, Johannsdottir H, Egilsson V, Barkardottir R, Johannsson O, Haraldsson K, Sandberg T, Holmberg E, Grönberg H, Olsson H, Borg Å, Vehmanen P, Eerola H, Heikkilä P, Pyrhönen S, Nevanlinna H.
Somatic deletions in hereditary breast cancers implicate 13q21 as a putative novel breast cancer susceptibility locus.
Proc Natl Acad Sci U S A, 97:9603-9608, 2000.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10944226 |
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Khan J, Bittner ML, Saal LH, Teichmann U, Azorsa DO, Gooden GC, Pavan WJ, Trent JM, Meltzer PS.
cDNA microarrays detect activation of a myogentic transcription program by the PAX3-FKHR fusion oncogene.
Proc Natl Acad Sci U S A, 96:13264-13269, 1999.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1055730 |
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Kim S, Dougherty E, Chen Y, Sivakumar K, Meltzer P, Trent JM, Bittner M.
Multivariate measurements of gene expression relationships.
Genomics, 67:201-9, 2000.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10903845 |
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Lange EM, Chen H, Brierley K, Perrone EE, Bock CH, Gillanders EM, Ray ME, Cooney KA.
Linkage analysis of 153 prostate cancer families over a 30-cM region containing the putative susceptibility locus HPCX.
Clinical Cancer Research, 5:4013-20, 1999.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10632333 |
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Pollock PM, Cohen-Solal K, Sood R, Namkoong J, Martino JJ, Koganti A, Zhu H, Robbins C, Makalowska I, Shin SS, Marin Y, Roberts KG, Yudt LM, Chen A, Cheng J, Incao A, Pinkett HW, Graham CL, Dunn K, Crespo-Carbone SM, Mackason KR, Ryan KB, Sinsimer D, Goydos J, Reuhl KR, Eckhaus M, Meltzer PS, Pavan WJ, Trent JM, Chen S.
Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia.
Nature Genetics, 34:108-12, 2003.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12704387 |
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Pollock PM, Harper UL, Hansen KS, Yudt LM, Stark M, Robbins CM, Moses TY, Hostetter G, Wagner U, Kakareka J, Salem G, Pohida T, Heenan P, Duray P, Kallioniemi O, Hayward NK, Trent JM, Meltzer PS.
High frequency of BRAF mutations in nevi.
Nature Genetics, 33:19-20, 2003.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12447372 |
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Powell IJ, Carpten J, Dunston G, Kittles R, Bennett J, Hoke G, Pettaway C, Weinrich S, Vijayakumar S, Ahaghotu CA, Boykin W, Mason T, Royal C, Baffoe-Bonnie A, Bailey-Wilson J, Berg K, Trent J, Collins F.
African-American heredity prostate cancer study: a model for genetic research.
J Natl Med Assoc, 93:120-3, 2001.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12653398 |
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Sarantaus L, Huusko P, Eerola H, Launonen V, Vehmanen P, Rapakko K, Gillanders E, Syrjäkoski K, Kainu T, Vahteristo P, Krahe R, Pääkkönen K, Hartikainen J, Blomqvist C, Löppönen T, Holli K, Ryynänen M, Bützow R, Borg A, Wasteson Arver B, Holmberg E, Mannermaa A, Kere J, Kallioniemi OP, Winqvist R, and Nevanlinna H.
Multiple founder effects and geographical clustering of BRCA1 and BRCA2 families in Finland.
Eur J Hum Genet, 8:757-63, 2000.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11039575 |
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Scacheri PC, Gillanders EM, Subramony SH, Vedanarayanan V, Crowe CA, Thakore N, Bingler M, Hoffman EP.
Novel mutations in collagen VI genes: expansion of the Bethlem myopathy phenotype.
Neurology, 58:593-602, 2002.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11865138 |
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Schleutker J, Matikainen M, Smith J, Koivisto P, Baffoe-Bonnie A, Kainu T, Gillanders E, Sankila R, Pukkala E, Carpten J, Stephan D, Tammela T, Brownstein M, Bailey-Wilson J, Trent J, Kallioniemi OP.
A genetic epidemiological study of hereditary prostate cancer (HPC) in Finland: frequent HPCX linkage in families with late-onset disease.
Clinical Cancer Research, 6:4810-5, 2000.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11156239 |
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Stephan DA, Howell GR, Teslovich TM, Coffey AJ, Smith L, Bailey-Wilson JE, Malechek L, Gildea D, Smith JR, Gillanders EM, Schleutker J, Hu P, Steingruber HE, Dhami P, Robbins CM, Makalowska I, Carpten JD, Sood R, Mumm S, Reinbold R, Bonner TI, Baffoe-Bonnie A, Bubendorf L, Heiskanen M, Kallioneimi OP, Baxevanis AD, Joseph SS, Zucchi I, Burk RD, Isaacs W, Ross MT, Trent JM.
Physical and transcript map of the hereditary prostate cancer region at Xq27.
Genomics, 79:41-50, 2002.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11827456 |
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Tranebjaerg L, Teslovich TM, Jones M, Barmada MM, Fagerheim T, Dahl A, Escolar DM, Trent JM, Gillanders EM, Stephan DA.
Genome-wide homozygosity mapping localizes a gene for autosomal recessive non-progressive infantile ataxia to 20q11-q13.
Hum Genet, 113:293-5, 2003.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12811539 |
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Walker GJ, Indsto JO, Sood R, Faruque MU, Hu P, Pollock PM, Duray P, Holland EA, Brown K, Kefford RF, Trent JM, Mann GJ, Hayward NK.
Deletion mapping suggests that the 1p22 melanoma susceptibility gene is a tumor suppressor localized to a 9-Mb interval.
Genes Chromosomes Cancer, 41:56-64, 2004.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15236317 |
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Weeraratna AT, Jiang Y, Hostetter G, Rosenblatt K, Duray P, Bittner M, Trent JM.
Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma.
Cancer Cell, 1:279-88, 2002.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1208686 |
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Xu J, for the International Consortium for Prostate Cancer Genetics (incl. Trent J).
Combined analysis of hereditary prostate cancer linkage to 1q24-25: Results from 772 hereditary prostate cancer families from the International Consortium for Prostate Cancer Genetics.
Am J Hum Genet, 66:945-957, 2000.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10712209 |
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Xu J, Langefeld CD, Zheng SL, Gillanders EM, Chang BL, Isaacs SD, Williams AH, Wiley KE, Dimitrov L, Meyers DA, Walsh PC, Trent JM, Isaacs WB.
Interaction effect of PTEN and CDKN1B chromosomal regions on prostate cancer linkage.
Hum Genet, 115:255-62, 2004.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15185141 |
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Xu J, Zheng SL, Komiya A, Mychaleckyj JC, Isaacs SD, Hu JJ, Sterling D, Lange EM, Hawkins GA, Turner A, Ewing CM, Faith DA, Johnson JR, Suzuki H, Bujnovszky P, Wiley KE, DeMarzo AM, Bova GS, Chang B, Hall MC, McCullough DL, Partin AW, Kassabian VS, Carpten JD, Bailey-Wilson JE, Trent JM, Ohar J, Bleecker ER, Walsh PC, Isaacs WB, Meyers DA.
Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk.
Nature Genetics, 32:321-5, 2002.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1224432 |
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Zhu G, Evans DM, Duffy DL, Montgomery GW, Medland SE, Gillespie NA, Ewen KR, Jewell M, Liew YW, Hayward NK, Sturm RA, Trent JM, Martin NG.
A genome scan for eye color in 502 twin families: most variation is due to a QTL on chromosome 15q.
Twin Res, 7:197-210, 2004.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15169604 |
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